Epigenomics-Based Diagnostics
نویسندگان
چکیده
منابع مشابه
Epigenomics-based diagnostics.
Epigenetic changes, especially methylation of DNA at the 5 position of cytosine, which occurs in cytosine/ guanine-rich regions (CpG islands), may have major effects on gene transcription. For example, it is known that extensive methylation at GC-rich regions of gene promoters or other areas can dramatically affect gene transcription and consequently the whole biology of a particular cell. Epig...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2010
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2010.148007